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NEW QUESTION 42
According to the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to ReduceAtherosclerotic Cardiovascular Risk in Adults, which of the following LDL cholesterol thresholds is an indication for high- intensity statin therapy?
- A. 150 mg/dL
- B. 130 mg/dL
- C. 190 mg/dL
- D. 100 mg/dL
- E. 200 mg/dL
Answer: C
Explanation:
Explanation
Statin therapy should be used as treatment in adults with primary LDL-C 190 mg/dL and age over 21 years.
Unless contraindicated, high-intensity statin therapy should be used.
NEW QUESTION 43
LN is 84 YOM who is in hospital for a back surgery. His height is 5 feet and 4 inches, weight 85 kg and NKDA.
His past medical history includes hypertension, diabetes mellitus, major depression, hypothyroidism and chronic back pain. Post-op day 1, LN's medication includes Dexamethasone 8mg iv q6h with taper dosing, Ondansetron 4mg iv q6h prn for N/V, Levothyroxine 0.075mg po daily, Lisinopril 10mg po daily, Citalopram
20mg po daily, Docusate sodium / Senna 1 tab po twice a day, Bisacodyl 10mg suppository daily prn for constipation, Famotidine 20mg iv q12hr, Metoclopramide 10mg iv q6h, Metformin 500mg po bid, D51/2NS with 20K at 125mls/hour and Hydromorphone PCA at 0.2mg/hour of basal rate, demand dose 0.1mg. lock-out every 6min, one hour limit 2.2mg/hour. Pertinent morning labs includes serum creatinine 1.4mg/dl, Mg 1.5mg/ dl, K 5.0mmol/L, Na 135mmol/L.
Which of the following medication's dose are adjusted for poor renal function?
- A. Ondansetron
- B. Lisinopril
- C. Famotidine
- D. Metoclopramide
- E. Citalopram
Answer: D
Explanation:
Explanation
Famotidine and Metoclopramide would need to be adjusted for poor renal function. Since his CrCl is less than
50, famotidine would need to be adjusted by decreasing the dose by 50% or increasing the interval to every 36 to 48 hours. Metoclopramide would also need to be adjusted by 50% of the normal dose since his CrCl is less than 40. ACEInhibitors and ARBs should be held if serum K is greater than 5.6 or there is a rise in serum creatinine greater than 30% after initiation.
NEW QUESTION 44
The rate that an outcome will occur given a particular exposure, compared to the rate of the outcome occurring in the absence of that exposure is definition of which of the following?
- A. Confidence Interval
- B. Prevelance rate
- C. Relative risk
- D. Incidence rate
- E. Odds ratio
Answer: C
Explanation:
RR = rate of an outcome occurring in an exposed group (treatment group/intervention group) divided by the rate of an outcome occurring in an unexposed group (control group) Ex: Relative Risk = Rate of UTI in patients taking drug XYZ / rate of UTI in patients not on drug XYZ Reference:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938757/
NEW QUESTION 45
What is the standard oral weekly dose of alendronate given to treat osteoporosis?
- A. 200mg
- B. 140mg
- C. 10mg
- D. 70mg
Answer: D
Explanation:
Explanation
The standard oral dose of alendronate in the treatment of osteoporosis is 70mg weekly - or 10mg per day.
NEW QUESTION 46
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